Speciality Requirements Student must complete 36 credit hours

Course Code	Course Name	Credit Hours	Prerequests
7760101	Pharmaceutical Research Methodology	2
Understanding and analyzing scientific data and results is an essential component of scientific research. This course will teach the student how to search for scientific results using various databases. Moreover, the course will cover how to structure a good research paper and criticize and review a scientific paper. Students will be taught the basic statistical analysis to design an appropriate experimental design. In the end, the course will also cover acceptable and unacceptable ethical behavior in scientific research.
7760102	Advanced Topics in Therapeutics	2
This course requires Ph.D. students to integrate concepts and skills with the knowledge derived from undergraduate and postgraduate studies, and apply them to a range of case scenarios and practical exercises that necessitate skills for critical thinking and problem-solving. This course provides a didactic framework for the advanced therapeutic management of particular diseases in various body systems, including cardiovascular disorders, central nervous system disorders, endocrine disorders, gastrointestinal disorders, respiratory disorders, oncology, and hematology. In addition, newly approved medications for important prevalent diseases are included.
7760103	Advanced Topics in Pharmacology	2
This course focuses on the molecular basis of receptor pharmacology, and the mechanisms of drug action at the molecular level. Receptor binding, isolation, and the application of molecular cloning methods are discussed. The course will also be focused on the discovery of molecular and cellular mechanisms of intracellular signaling, and the translation of the molecular findings in the development of novel therapeutic agents.
7760104	Drug Disposition	2
This course is designed to provide Ph.D. students with an understanding of advanced principles of drug metabolism and disposition and is focused on understanding the importance of absorption, distribution, metabolism, and excretion of drugs during drug discovery and how these influence drug pharmacokinetics and pharmacodynamics. This course covers the principle topics in the pharmacokinetics and pharmacodynamics required for applied therapeutics and practice. Core topics include monoexponential kinetics; multiexponential kinetics; intravenous infusions; multiple dosing and dosage regimen design; non-linear kinetics; drug absorption; bioequivalence; drug distribution; drug metabolism; drug elimination; metabolite kinetics; pharmacodynamics; and toxicology. Advanced topics cover factors affecting drug efficacy including drug interactions and sources of variability in therapeutic outcomes. Applied topics include therapeutic drug monitoring and drug individualization, and adverse drug reactions.
7760105	Advanced Dosage Forms Design	2
This interdisciplinary course describes the principles in physical chemistry and drug transport, aiming for advances in formulation, drug targeting, and multi-modal therapy. Also to design, synthesize, characterize and analyze novel materials and drug delivery systems and design and develop technologies related to therapeutic distribution in the body. Delivery research includes the solid-state chemistry of drugs, nano-pharmacy, biocompatibility, molecular recognition, computational chemistry, pharmacokinetics, and molecular imaging. Controlled drug delivery systems utilizing polymers, synthesis of different types of devices, the delivery expected from these devices, and mathematical modeling of delivery systems.
7760106	Drug Discovery and Development	2
The course will provide the theoretical principles of the drug design and development process. The progress of pharmaceutical sciences in the drug discovery system, starting with the classical drug design and optimizing the drug structure, followed by understanding the structure of the macromolecules as a drug target, continuing the modern drug discovery techniques such as docking and in silico drug design.
7760107	Qualifying Exam	0
It is an exam conducted for all Ph.D. students of all compulsory courses to evaluate their capability to build up sufficient knowledge of the program.
7760108	Thesis	24
The student will prepare his/her research proposal, and present it in front of the Ph.D. committee. After the acceptance, he/she will carry out the research of the selected project, prepare the thesis, and defend it.

Speciality Optional Requirements Student must complete 12 credit hours

Course Code	Course Name	Credit Hours	Prerequests
7760110	Advanced Pharmaceutical Natural Products	2
This Ph.D. course is designed to provide students required information about medicinal plants and other important natural products due to the increased worldwide demand for experts in the development of natural medicine. This course provides an introduction to plant systematics. Significant medicinal plants and natural medicines will be discussed. Important classes of compounds (secondary metabolites) from nature will be emphasized, and stress will be put on classification, occurrence, nomenclature, and pharmaceutical perspectives. Also, the course will discuss the use of natural products as medicines or as starting materials for drugs.
7760111	Advanced Cosmeceutical Science	2
The course discusses topics including structure and functions of skin; classification of skin conditions and skin problems; research and development for skin care products; importance and applications; formulation and evaluation; cosmetic laws; social issues related to cosmetic products; in vitro testing; animal and human testing; claims substantiation; sensory evaluation; marketing and business plan for skin cosmetic products; regulation on skin cosmetic products.
7760112	Selected Topics in Pharmaceutical Manufacturing	2
This course addresses the rational design and formulation of dosage forms, and the processes and equipment in their large-scale manufacture. Consideration is on how the interplay of formulation and process variables affects both the manufacturability of the dosage form and its performance as a drug delivery system.
7760113	Advances in Drug Synthesis	2
The course will overlay the principles of organic chemistry in the synthesis and design of drugs. Different synthetic approaches will be covered such as the utilization of the retrosynthesis approach in the synthesis of the drug, the use of various protecting groups in drug synthesis, solid phase synthesis, and combinatorial chemistry will be discussed.
7760114	Advanced Pharmaceutical Nanotechnology	2
The course will cover the advances of nanotechnology in pharmaceutical applications. The course will discuss the different nanomaterials that could be used in the pharmaceutical industry. Moreover, the various techniques used to formulate the drugs in nanomaterials will be discussed. Finally, the applications of nanomaterials in pharmaceutical applications will be covered.
7760115	Pharmacogenomics	2
This is a course designed for the pharmaceutical science Ph.D. program offered by the Faculty of Graduate studies a?? An-Najah National University. This course introduces Ph.D. students to the emerging fields of pharmacogenomics and personalized dose management. The course helps students build their knowledge and understanding of these new fields and develop professional evidence-based approaches to keep pace with these fast-moving areas into the future. Topics covered will include basic pharmacokinetics and pharmacodynamics, genetics of drugmetabolizing enzymes, genetics of drug receptors, individual differences in targeted and nontargeted drug responses, cardiovascular, central nervous system, infectious disease pharmacology, and genetics of cancer treatment. The course content also includes ethical/legal and regulatory topics.
7760116	Quality Control and Assurance in the Pharmaceutical Industry	2
The Pharmaceutical Quality Control and Quality Assurance course provides students with comprehensive knowledge and skills in the fields of Pharmaceutical Analysis, Quality Assurance, and Regulatory Affairs. All topics are discussed with experts from the pharmaceutical industry. Through this course, students have the opportunity to work in a state-of-the-art laboratory that simulates working in a GMP environment.
7760117	Pharmaceutical Bioanalysis	2
It is an advanced course in bioanalysis that provides quality, scientific instruction in bioanalytical fields with health applications. The goal of the course is to equip students with the information, abilities, and strong laboratory skills necessary for the bioanalyst to address analytical problems in the fields of medicine, food science, and environmental science. Students will get an understanding of the concepts underlying contemporary bioanalytical methods and how they are applied in, pharmaceuticals, environment, biotechnology, and other relevant industries. This course will address topics including impurity identification, extractable and leachable tests, in vitro and in vivo studies, sample analysis for the chemical and biological industry, bioanalytical method validations, and bioanalysis of clinical trial samples under GCLP protocols.
7760118	Advanced Spectroscopy	2
The advanced spectroscopic course will cover a variety of chemical and biological research and also serve as an important analytical tool. This course will expose students to some of the essential ideas, tools, and procedures that control spectroscopic observations, allowing them to define chemical structure and composition. This course will provide students with state-of-the-art knowledge of spectroscopy. It will provide high-level scientific knowledge and training, as well as access to some research-grade equipment that is available at our university. The course material will mainly focus on structural characterization. Other spectroscopic characterization such as fast reactions, in situ spectroscopy, and imaging will be also taught. Moreover, this course will cover many advanced topics on spectroscopy techniques such as mass spectroscopy, Nuclear Magnetic Resonance (NMR), optical spectroscopy, X-ray diffraction, synchrotron radiation, and its applications, structural inorganic chemistry, surface Spectroscopy: Methods and Applications
7760119	Clinical Management of Infectious Diseases	2
This course provides advanced information on the major infectious diseases that are of public health interest. The course is designed to introduce students to the underlying principles of infectious disease management and updated treatment guidelines. By the end of this students will be able to develop rational drug therapy plans for patients and provide suitable pharmaceutical care for a group of infectious diseases. In addition, students will be taught the rational use of anti-microbial agents by discussing with them selected clinical case studies and reports.
7760120	Advanced Practice in Primary Care	2
This course is designed to provide an advanced understanding of clinical management in primary care and to develop knowledge and understanding of a range of acute and chronic conditions, exploring presentations and clinical management across all age groups. In addition to an understanding of referral pathways and processes, national policies and guidelines, clinical targets, and the role of pharmacists in primary care and consultation. It aims to help students in developing clinical skills and leadership abilities to become flexible practitioners able to respond to challenges.
7760121	Pharmacology bioassay laboratory	2
This course is designed to introduce Ph.D. students to the standard techniques utilized in pharmacology experiments for exploring the effects of a certain treatment on a biological system at the molecular level. The students will learn the basics of cell and tissue culture, treatment applications, cellular structure, protein, DNA and RNA and isolation, Bradford protein assay, western blotting, PCR, qPCR, and immuno-/ fluorescence staining of cells.
7760122	Therapeutics of Common Diseases	2
The course covers pharmacotherapeutic regimens for some important prevalent diseases, including pharmacotherapeutic and non-pharmacological approaches. Common health problems such as infectious diseases, cardiovascular diseases, respiratory diseases, skin diseases, etc, and their therapeutic approaches will be discussed. In addition, in this course, physiological, pharmacological, and therapeutic considerations will be included with relevance to special populations such as pediatric patients, geriatric patients, and pregnant and nursing women.
7760123	Clinical Toxicology	2
This course aims to familiarize students enrolled in the Pharmaceutical Ph.D. program at An-Najah National University with the evidence-based best practice applications of the clinical toxicology discipline. This course will introduce students to clinical applications through case studies and evidence-based approaches to the diagnosis and treatment of poisoned patients. The course will also emphasize the use of poison and drug information and literature evaluation skills. The objective of this course is to cultivate critical thinking and literature evaluation abilities in the field of clinical toxicology.
7760124	Advanced Pharmacoeconomics	2
Advanced pharmacoeconomics course is an interdisciplinary course that introduces students to the main concepts of pharmacoeconomics. It is considered an aid to better health care management. It allows students to gain practical experience in the development of economic evaluation of pharmaceuticals. This exciting area of study identifies quality patient care by balancing economic, humanistic and clinical outcomes. It provides insights that guide optimal resource allocation. Pharmacoeconomic data are used by clinicians, health systems, health insurers and payers, policy-makers, health technology assessment agencies, and patients. In addition, the topics covered included assessment of effective data, costs, quality of life assessment and the development of economic models of cost-effectiveness. In addition, the rational use of medication and the appropriate drug use according to the clinical need with the lowest cost to patients and the community are also studied.